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A novel potent metal-binding NDM-1 inhibitor was identified by fragment virtual, SPR and NMR screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 9, 页码: 9
Authors:  Guo, Huifang;  Cheng, Kai;  Gao, Yan;  Bai, Weiqi;  Wu, Cai;  He, Wei;  Li, Conggang;  Li, Zhuorong
Favorite  |  View/Download:4/0  |  Submit date:2020/07/02
NDM-1  Metal-binding pharmacophore  Fragment-based drug design  SPR  NMR  
Rational modulation of the enzymatic intermediates for tuning the phosphatase activity of histidine kinase HK853 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 卷号: 523, 期号: 3, 页码: 733-738
Authors:  Ji, Shixia;  Luo, Liang;  Li, Conggang;  Liu, Maili;  Liu, Yixiang;  Jiang, Ling
Favorite  |  View/Download:4/0  |  Submit date:2020/07/02
Histidine kinase  Two-component system  Phosphatase  Near attack conformation  Dynamics  
realt1aneffectiveapproachfort1noisesuppressioninnmrspectroscopybasedonresamplingalgorithm 期刊论文
chinesejournalofchemistry, 2020, 卷号: 38, 期号: 1, 页码: 77
Authors:  Song Linhong;  Wang Jiannan;  Su Xuncheng;  Zhang Xu;  Li Conggang;  Zhou Xin;  Yang Daiwen;  Jiang Bin;  Liu Maili
Favorite  |  View/Download:9/0  |  Submit date:2020/07/02
Effect of Substituent Size and Isomerization on the Polymorphism of 2-(Naphthalenylamino)-benzoic Acids 期刊论文
CRYSTAL GROWTH & DESIGN, 2019, 卷号: 19, 期号: 7, 页码: 3694-3703
Authors:  Liu, Yuting;  Zhang, Mingtao;  Xu, Danrui;  Parkin, Sean;  Li, Tonglei;  Li, Conggang;  Yang, Zhaoyong;  Yu, Faquan;  Long, Sihui
Favorite  |  View/Download:15/0  |  Submit date:2019/10/14
Protein stability analysis in ionic liquids by F-19 NMR 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 19, 页码: 4929-4935
Authors:  Cheng, Kai;  Wu, Qiong;  Jiang, Ling;  Liu, Maili;  Li, Conggang
Favorite  |  View/Download:14/0  |  Submit date:2019/10/14
Ionic liquids  Protein stability quantification  F-19 NMR  
Membrane-mediated disorder-to-order transition of SNAP25 flexible linker facilitates its interaction with syntaxin-1 and SNARE-complex assembly 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 7, 页码: 7985-7994
Authors:  Jiang, Xin;  Zhang, Zeting;  Cheng, Kai;  Wu, Qiong;  Jiang, Ling;  Pielak, Gary J.;  Liu, Maili;  Li, Conggang
Favorite  |  View/Download:13/0  |  Submit date:2019/10/14
prefusion state  protein NMR  intrinsically disordered region  circular dichroism  
Structure-guided post-SELEX optimization of an ochratoxin A aptamer 期刊论文
NUCLEIC ACIDS RESEARCH, 2019, 卷号: 47, 期号: 11, 页码: 5963-5972
Authors:  Xu, Guohua;  Zhao, Jiajing;  Liu, Na;  Yang, Minghui;  Zhao, Qiang;  Li, Conggang;  Liu, Maili
Favorite  |  View/Download:9/0  |  Submit date:2019/10/14
Chemical shift assignments of the catalytic and ATP-binding domain of HK853 from Thermotoga maritime 期刊论文
BIOMOLECULAR NMR ASSIGNMENTS, 2019, 卷号: 13, 期号: 1, 页码: 173-176
Authors:  Zhou, Yuan;  Liu, Xinghong;  Li, Conggang;  Liu, Maili;  Jiang, Ling;  Liu, Yixiang
Favorite  |  View/Download:21/0  |  Submit date:2019/06/24
Chemical shift assignment  NMR  HK853(CA)  Secondary structure  HSQC  
Structural Basis for the Inhibition of the Autophosphorylation Activity of HK853 by Luteolin 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 11
Authors:  Zhou, Yuan;  Huang, Liqun;  Ji, Shixia;  Hou, Shi;  Luo, Liang;  Li, Conggang;  Liu, Maili;  Liu, Yixiang;  Jiang, Ling
Favorite  |  View/Download:32/0  |  Submit date:2019/06/24
two-component system  histidine kinase  luteolin  ATP  NMR  molecular docking  inhibition  
组氨酸激酶hk853酸碱调控机制的nmr研究 期刊论文
分析测试学报, 2019, 卷号: 038, 期号: 005, 页码: 503
Authors:  吉仕夏;  刘乙祥;  姜红鹰;  李从刚;  姜凌;  刘买利
Favorite  |  View/Download:11/0  |  Submit date:2020/01/14