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Targeting the Human Genome-Microbiome Axis for Drug Discovery: Inspirations from Global Systems Biology and Traditional Chinese Medicine 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2012, 卷号: 11, 期号: 7, 页码: 3509-3519
Authors:  Zhao, Liping;  Nicholson, Jeremy K.;  Lu, Aiping;  Wang, Zhengtao;  Tang, Huiru;  Holmes, Elaine;  Shen, Jian;  Zhang, Xu;  Li, Jia V.;  Lindon, John C.
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Drug Discovery  Global Systems Biology  Gut Microbiome  Superorganism  Traditional Chinese Medicine  
Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2012, 卷号: 11, 期号: 2, 页码: 631-642
Authors:  Cazier, Jean-Baptise;  Kaisaki, Pamela J.;  Argoud, Karene;  Blaise, Benjamin J.;  Veselkov, Kirill;  Ebbels, Timothy M. D.;  Tsang, Tsz;  Wang, Yulan;  Bihoreau, Marie-Therese;  Mitchell, Steve C.;  Holmes, Elaine C.;  Lindon, John C.;  Scott, James;  Nicholson, Jeremy K.;  Dumas, Marc-Emmanuel;  Gauguier, Dominique
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Genetics  Metabonomics  Functional Genomics  Quantitative Trait Locus  Nmr Spectroscopy  Glycerate  Glycerate Kinase  
Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni 期刊论文
PARASITES & VECTORS, 2011, 卷号: 4, 期号: 39, 页码: 179-179
Authors:  Li, Jia V.;  Saric, Jasmina;  Wang, Yulan;  Keiser, Jennifer;  Utzinger, Juerg;  Holmes, Elaine
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Metabonomic Investigation of Single and Multiple Strain Trypanosoma brucei brucei Infections 期刊论文
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2011, 卷号: 84, 期号: 1, 页码: 91-98
Authors:  Li, Jia V.;  Saric, Jasmina;  Wang, Yulan;  Utzinger, Jurg;  Holmes, Elaine;  Balmer, Oliver;  E Balmer,O
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Systems parasitology: effects of Fasciola hepatica on the neurochemical profile in the rat brain 期刊论文
MOLECULAR SYSTEMS BIOLOGY, 2010, 卷号: 6, 期号: 1, 页码: 396-396
Authors:  Saric, Jasmina;  Li, Jia V.;  Utzinger, Juerg;  Wang, Yulan;  Keiser, Jennifer;  Dirnhofer, Stephan;  Beckonert, Olaf;  Sharabiani, Mansour T. A.;  Fonville, Judith M.;  Nicholson, Jeremy K.;  Holmes, Elaine
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Brain  Fasciola Hepatica  Immunology  Metabolic Profiling  Nuclear Magnetic Resonance Spectroscopy  
Metabolic alterations in the hamster co-infected with Schistosoma japonicum and Necator americanus 期刊论文
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2010, 卷号: 40, 期号: 6, 页码: 695-703
Authors:  Wu, Jun-Fang;  Holmes, Elaine;  Xue, Jian;  Xiao, Shu-Hua;  Singer, Burton H.;  Tang, Hui-Ru;  Utzinger, Juerg;  Wang, Yu-Lan
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Co-infection  Hamster  Metabonomics  Necator Americanus  Nmr Spectroscopy  Schistosoma Japonicum  
Advances in Metabolic Profiling of Experimental Nematode and Trematode Infections 期刊论文
ADVANCES IN PARASITOLOGY, VOL 73, 2010, 卷号: 73, 期号: 1, 页码: 373-404
Authors:  Wang, Yulan;  Li, Jia V.;  Saric, Jasmina;  Keiser, Jennifer;  Wu, Junfang;  Utzinger, Juerg;  Holmes, Elaine;  Zhou, XN;  Bergquist, R;  Olveda, R;  Utzinger, J
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High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues 期刊论文
NATURE PROTOCOLS, 2010, 卷号: 5, 期号: 6, 页码: 1019-1032
Authors:  Beckonert, Olaf;  Coen, Muireann;  Keun, Hector C.;  Wang, Yulan;  Ebbels, Timothy M. D.;  Holmes, Elaine;  Lindon, John C.;  Nicholson, Jeremy K.
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Systems Metabolic Effects of a Necator americanus Infection in Syrian Hamster 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2009, 卷号: 8, 期号: 12, 页码: 5442-5450
Authors:  Wang, Yulan;  Xiao, Shu-Hua;  Xue, Jian;  Singer, Burton H.;  Utzinger, Juerg;  Holmes, Elaine;  Wang, YL (reprint author), Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Ctr Magnet Resonance, Wuhan 430071, Peoples R China.
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Hookworm  Necator Americanus  Hamster  Metabolic Profiling  Microbiota  (1)h Nmr Spectroscopy  Multivariate Data Analysis  
Panorganismal Metabolic Response Modeling of an Experimental Echinostoma caproni Infection in the Mouse 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2009, 卷号: 8, 期号: 8, 页码: 3899-3911
Authors:  Saric, Jasmina;  Li, Jia V.;  Wang, Yulan;  Keiser, Jennifer;  Veselkov, Kirill;  Dirnhofer, Stephan;  Yap, Ivan K. S.;  Nicholson, Jeremy K.;  Holmes, Elaine;  Utzinger, Juerg;  Utzinger, J (reprint author), Swiss Trop Inst, Dept Publ Hlth & Epidemiol, CH-4002 Basel, Switzerland.
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Biomarker  Cluster Analysis  Echinostoma Caproni  Hierarchical Analysis  Magic Angle Spinning  Metabolic Profiling  Nmr Spectroscopy  Systemic Effect