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A NMR-based drug screening strategy for discovering active substances from herbal medicines: Using Radix Polygoni Multiflon as example 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 254, 页码: 8
Authors:  Wan, Hong;  Tian, Yafeng;  Jiang, Haipeng;  Zhang, Xu;  Ju, Xiulian
Favorite  |  View/Download:4/0  |  Submit date:2020/07/02
NMR-Based drug screening  Herbal medicines  Radix Polygoni Multifiori  Ligand-detected experiments  Saturation transfer difference spectrum(STD)  Fatty acid binding protein 4 (FABP(4))  HPLC-SPE-NMR  
Innovation Fund of Hubei Collaborative Innovation Center for Bioactive Polypeptide Diabetes Drugs 项目
资助机构: Innovation Fund of Hubei Collaborative Innovation Center for Bioactive Polypeptide Diabetes Drugs, 2020-
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Favorite  |  View/Download:5/0  |  Submit date:2020/07/02
All-atom structure ensembles of islet amyloid polypeptides determined by enhanced sampling and experiment data restraints 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2019, 卷号: 87, 期号: 7, 页码: 541-550
Authors:  Su, Xinyue;  Wang, Ke;  Liu, Na;  Chen, Jiawen;  Li, Yong;  Duan, Mojie
Favorite  |  View/Download:11/0  |  Submit date:2019/10/14
aggregation  chemical shift restraint  islet amylod polypeptide  metadynamics  
Optimization of band-selective homonuclear dipolar recoupling in solid-state NMR by a numerical phase search 期刊论文
JOURNAL OF CHEMICAL PHYSICS, 2019, 卷号: 150, 期号: 15, 页码: 14
Authors:  Zhang, Zhengfeng;  Liu, Hui;  Deng, Jing;  Tycko, Robert;  Yang, Jun
Favorite  |  View/Download:25/0  |  Submit date:2019/06/24
Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health 项目
资助机构: Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 2019-
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Favorite  |  View/Download:8/0  |  Submit date:2019/06/24
Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis 期刊论文
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2018, 卷号: 54, 页码: 28-34
Authors:  Tian, Yuan;  Nichols, Robert G.;  Cai, Jingwei;  Patterson, Andrew D.;  Cantorna, Margherita T.
Favorite  |  View/Download:24/0  |  Submit date:2018/11/05
Vitamin a  Microbiota  Short-chain Fatty Acids  Diabetes  Metabolomics  
Fecal Metabolomics of Type 2 Diabetic Rats and Treatment with Gardenia jasminoides Ellis Based on Mass Spectrometry Technique 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 卷号: 66, 期号: 6, 页码: 1591-1599
Authors:  Zhou, Yuan;  Men, Lihui;  Pi, Zifeng;  Wei, Mengying;  Song, Fengrui;  Zhao, Chunfang;  Liu, Zhiqiang
Favorite  |  View/Download:28/0  |  Submit date:2018/11/05
G. Jasminoides  Fecal Metabolomics  Uplc-qtoe-ms  Type 2 Diabetes  
Metabolic profile of visual cortex in diabetic rats measured with in vivo proton MRS 期刊论文
NMR IN BIOMEDICINE, 2017, 卷号: 30, 期号: 11
Authors:  Li, Shuang;  Wang, Xinghua;  Yang, Junjie;  Lei, Hao;  Wang, Xuxia;  Xiang, Yi
Favorite  |  View/Download:27/0  |  Submit date:2018/11/05
Diabetes  Metabolism  Mrs  Retinal Ganglion Cells  Visual Cortex  
Structural Properties of Human IAPP Dimer in Membrane Environment Studied by All-Atom Molecular Dynamics Simulations 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
Authors:  Liu, Na;  Duan, Mojie;  Yang, Minghui
Favorite  |  View/Download:27/0  |  Submit date:2017/12/06
Structural Properties of Human IAPP Dimer in Membrane Environment Studied by All-Atom Molecular Dynamics Simulations 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
Authors:  Liu, Na;  Duan, Mojie;  Yang, Minghui
Favorite  |  View/Download:29/0  |  Submit date:2017/12/06