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Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins
Chen, Zong-Yun1; Zeng, Dan-Yun2; Hu, You-Tian1; He, Ya-Wen1; Pan, Na3; Ding, Jiu-Ping3; Cao, Zhi-Jian1; Liu, Mai-Li2; Li, Wen-Xin1; Yi, Hong1; Jiang, Ling2; Wu, Ying-Liang1
2012-04-12
Source PublicationPLOS ONE
Volume7Issue:4
SubtypeArticle
AbstractBackground: Although the basic scorpion K+ channel toxins (KTxs) are well-known pharmacological tools and potential drug candidates, characterization the acidic KTxs still has the great significance for their potential selectivity towards different K+ channel subtypes. Unfortunately, research on the acidic KTxs has been ignored for several years and progressed slowly.
WOS HeadingsScience & Technology
DOI10.1371/journal.pone.0035154
WOS KeywordCA2+-ACTIVATED K+ CHANNELS ; TRANSCRIPTOME ANALYSIS ; THERAPEUTIC TARGET ; KV1.3 CHANNELS ; ANIMAL TOXINS ; NMR STRUCTURE ; HIGH-AFFINITY ; MAXI-K ; INHIBITOR ; VENOM
Indexed BySCI
Language英语
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000305338600067
Citation statistics
Cited Times:24[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.apm.ac.cn/handle/112942/1600
Collection磁共振基础研究部
Affiliation1.Wuhan Univ, State Key Lab Virol, Coll Life Sci, Wuhan 430072, Peoples R China
2.Chinese Acad Sci, Wuhan Ctr Magnet Resonance, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Inst Phys & Math, Wuhan, Peoples R China
3.Huazhong Univ Sci & Technol, Key Lab Mol Biophys, Minist Educ, Coll Life Sci & Technol, Wuhan 430074, Hubei, Peoples R China
Recommended Citation
GB/T 7714
Chen, Zong-Yun,Zeng, Dan-Yun,Hu, You-Tian,et al. Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins[J]. PLOS ONE,2012,7(4).
APA Chen, Zong-Yun.,Zeng, Dan-Yun.,Hu, You-Tian.,He, Ya-Wen.,Pan, Na.,...&Wu, Ying-Liang.(2012).Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins.PLOS ONE,7(4).
MLA Chen, Zong-Yun,et al."Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins".PLOS ONE 7.4(2012).
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