WIPM OpenIR
Interactions between amyloid beta peptide and lipid membranes
Niu, Zheng1,2; Zhang, Zhengfeng1; Zhao, Weijing1; Yang, Jun1
2018-09-01
Source PublicationBIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
ISSN0005-2736
Volume1860Issue:9Pages:1663-1669
SubtypeReview
AbstractThe presence of amyloid plaques in the brain is a typical characteristic of Alzheimer's disease (AD). Amyloid plaques are formed from the deposits of aggregated amyloid beta peptide (A beta). The toxicity induced by A beta aggregates is correlated with A beta-membrane interactions. The mutual influences between aggregation and membranes are complicated and unclear. In recent years advanced experiments and findings are emerging to give us more detailed information on A beta-membrane interactions. In this review, we mainly focus on the A beta-membrane interactions and membrane-induced A beta structures. The mechanism of A beta-membrane interactions is also summarized, which provides insights into the prevention and treatment of AD.
KeywordAlzheimer's Disease Beta-amyloid Peptide Fibrillation Phospholipids Membrane Disruption Solid-state Nuclear Magnetic Resonance
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Funding OrganizationNational Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803) ; National Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803) ; National Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803) ; National Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803)
DOI10.1016/j.bbamem.2018.04.004
WOS KeywordALZHEIMERS-DISEASE ; A-BETA ; METAL-IONS ; GANGLIOSIDE CLUSTERS ; SECONDARY NUCLEATION ; PROTEIN AGGREGATION ; MECHANISTIC INSIGHT ; MOLECULAR-STRUCTURE ; CHANNEL FORMATION ; FIBRIL FORMATION
Indexed BySCI
Language英语
Funding OrganizationNational Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803) ; National Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803) ; National Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803) ; National Natural Science Foundation of China(21173259 ; National Natural Science Foundation of China(21173259 ; 21405171 ; 21405171 ; 21425523 ; 21425523 ; 31627803) ; 31627803)
WOS Research AreaBiochemistry & Molecular Biology ; Biophysics
WOS SubjectBiochemistry & Molecular Biology ; Biophysics
WOS IDWOS:000442333600008
PublisherELSEVIER SCIENCE BV
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.wipm.ac.cn/handle/112942/13041
Collection中国科学院武汉物理与数学研究所
Corresponding AuthorYang, Jun
Affiliation1.Chinese Acad Sci, Key Lab Magnet Resonance Biol Syst, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Ctr Magnet Resonance,Wuhan Inst Phys & Math, Wuhan 430071, Hubei, Peoples R China
2.Tech Univ Munich, Dept Chem, D-85748 Garching, Germany
Recommended Citation
GB/T 7714
Niu, Zheng,Zhang, Zhengfeng,Zhao, Weijing,et al. Interactions between amyloid beta peptide and lipid membranes[J]. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES,2018,1860(9):1663-1669.
APA Niu, Zheng,Zhang, Zhengfeng,Zhao, Weijing,&Yang, Jun.(2018).Interactions between amyloid beta peptide and lipid membranes.BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES,1860(9),1663-1669.
MLA Niu, Zheng,et al."Interactions between amyloid beta peptide and lipid membranes".BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1860.9(2018):1663-1669.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Niu, Zheng]'s Articles
[Zhang, Zhengfeng]'s Articles
[Zhao, Weijing]'s Articles
Baidu academic
Similar articles in Baidu academic
[Niu, Zheng]'s Articles
[Zhang, Zhengfeng]'s Articles
[Zhao, Weijing]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Niu, Zheng]'s Articles
[Zhang, Zhengfeng]'s Articles
[Zhao, Weijing]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.